Maximin and maximin-efficient event-related fMRI designs under a nonlinear model

Maximin and Maximin-efficient Event-related Fmri Designs under a Nonlinear Model by Ming-hung Kao,

Previous studies on event-related functional magnetic resonance imaging experimental designs are primarily based on linear models, in which a known shape of the hemodynamic response function (HRF) is assumed. However, the HRF shape is usually uncertain at the design stage. To address this issue, we consider a nonlinear model to accommodate a wide spectrum of feasible HRF shapes, and propose eff...

Maximin and Maximin - Efficient Event - Related Fmri Designs under a Nonlinear Model

Previous studies on event-related functional magnetic resonance imaging experimental designs are primarily based on linear models, in which a known shape of the hemodynamic response function (HRF) is assumed. However, the HRF shape is usually uncertain at the design stage. To address this issue, we consider a nonlinear model to accommodate a wide spectrum of feasible HRF shapes, and propose eff...

Maximin Optimal Designs for the Compartmental Model

Orthogonal-maximin Latin Hypercube Designs

A randomly generated Latin hypercube design (LHD) can be quite structured: the variables may be highly correlated or the design may not have good space-filling properties. There are procedures for finding good LHDs by minimizing the pairwise correlations or by maximizing the inter-site distances. In this article we show that these two criteria need not be in close agreement. We propose a multi-...

Bounds for Maximin Latin Hypercube Designs

Latin hypercube designs (LHDs) play an important role when approximating computer simulation models. To obtain good space-filling properties, the maximin criterion is frequently used. Unfortunately, constructing maximin LHDs can be quite time-consuming when the number of dimensions and design points increase. In these cases, we can use approximate maximin LHDs. In this paper, we construct bound...